Efficacy of antidepressants in adults.

نویسندگان

  • Joanna Moncrieff
  • Irving Kirsch
چکیده

http://bmj.com/cgi/content/full/331/7509/155 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/331/7509/155/DC1 "References w1 w20" References http://bmj.com/cgi/content/full/331/7509/155#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/331/7509/155#BIBL This article cites 15 articles, 7 of which can be accessed free at:

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This meta-analysis aims to assess the efficacy and safety of SSRIs and TCAs in treatment of PD. A computer-base search was conducted of Pubmed, MEDLINE, EMBASE, Cochrane Controlled Trails Register (CCTR) up to December 2011. The random controlled clinic trials about SSRIs and TCAs in PD treatment were collected. Statistical analysis was completed using Review Manager, version 5.0. Five clinic c...

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A systematic review of newer pharmacotherapies for depression in adults: evidence report summary.

BACKGROUND Depressive disorders are persistent, recurring illnesses that cause great suffering for patients and their families. PURPOSE To evaluate the benefits and adverse effects of newer pharmacotherapies and herbal treatments for depressive disorders in adults and adolescents. DATA SOURCES English-language and non-English-language literature from 1980 to January 1998 was identified from...

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The Efficacy of N-Acetyl-Cysteine (NAC) Supplementation in FST Model for Screening Antidepressants

Introduction: The model for screening antidepressant-like activity in pre-clinical drug studies include, rat forced swimming test (FST). The reports on N-acetylcysteine (NAC) as an antioxidant supplement in stress related disorder is well documented. This study was aimed at potential antidepressant mechanism of N- Acetyl Cysteine (NAC), a glutamate precursor on FST animal model for screening an...

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Antidepressants in the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis

BACKGROUND Antidepressants have been empirically used in the treatment of functional dyspepsia (FD). However, results from recent clinical trials investigating their efficacy are conflicting. The aim of this study is to evaluate the efficacy of antidepressants in the management of FD in adults. METHODS Databases of MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and BIOSIS...

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عنوان ژورنال:
  • BMJ

دوره 331 7509  شماره 

صفحات  -

تاریخ انتشار 2005